It takes one pimple to ruin a good day. And luckily, it takes one good spot treatment to ruin a pimple.
Spot treatments are exactly what they sound like: one-off treatments that target individual pimples or blemishes as they arise; these can even include stubborn dark spots that refuse to disappear in the wake of a blemish.
Many acne-prone people use products that target the entire face, like a salicylic acid cleanser or serum, or an oil-free moisturizer to prevent clogging. These individuals are probably more cognizant of how each product can clog (or unclog) pores. But for anyone with a periodic pimple — or for acne-prone people who can usually keep the biggest, baddest ones at bay — every so often, there’s a blemish that simply refuses to stay quiet. You can feel it under there, stewing and steaming, or you wake up with it, practically ready to burst already. They’re sneaky like that. And what’s not sneaky is the open wound or active volcano they leave on your face.
That’s where the spot treatments come in handy. They can contain any variety of bacteria-fighting, pore-clearing, or complexion-brightening ingredients. Below is a roster of the best spot treatments, each with some unique way of disappearing, calming, or healing blemishes. You may want to stock up on a few of them, given the range of blemishes that can pop up at any time.
Best Overall Spot Treatment: Mighty Patch Hydrocolloid Patches

The Original
Familiarize yourself with the miracle of hydrocolloid patches. They are little stickers that you leave on for 6 hours or overnight (sometimes with microdarts to seep deep into a cystic pimple, sometimes flat-bottomed to focus on whiteheads). They soak up the oil and grime beneath the surface of the skin, and Mighty Patch sells one of the more affordable and more reliable patches in the game. They are discreet enough for daytime wear, and durable enough for day or night. Simply apply it to the spot (after cleansing), and after the 6-8-hour wait, you’ll have a less rabid pimple, with much of its goo now on the underside of the sticker. They’ll spare you any need to pop (and thus any week-long haunting / dark-spot agony after the acne is gone).